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NISH (NITAG Support Hub) 13: Typhoid Conjugate Vaccine (TCV) : Domain 2: Benefits and Harms

This Library Guide is a collection of useful documents & evidence on the safety, efficacy, effectiveness and impact of the Typhoid Conjugate Vaccine (TCV) to support NITAG members and other policy makers throughout Africa with making evidence-based recom

TCV and "benefits and harms"

BATOOL, R. (n.d.). Impact Assessment of Typhoid Conjugate Vaccine in South Asian Slumshttps://trepo.tuni.fi/bitstream/handle/10024/224785/978-952-03-3847-3.pdf?sequence=2

Buzilă, E. R., Dorneanu, O. S., Trofin, F., Sima, C. M., & Iancu, L. S. (2025). Assessing Salmonella Typhi Pathogenicity and Prevention: The Crucial Role of Vaccination in Combating Typhoid Fever. International Journal of Molecular Sciences, 26(9), 3981.https://doi.org/10.3390/ijms26093981

Demirtas, E. D., Barnard, R., Lee, J., & Jit, M. (2025). A systematised review and evidence synthesis on the broader societal impact of vaccines against Salmonella. Npj Vaccines, 10(1), 21. https://doi.org/10.1038/s41541-024-01034-4

Emary, K., Bentsi-Enchill, A. D., Giersing, B. K., Gordon, M., Dale, H., Chirwa, E. B., Johnston, P., MacLennan, C. A., Kariuki, S., & Excler, J.-L. (2025). Landscape analysis of invasive non-typhoidal salmonella (iNTS) disease and iNTS vaccine use case and demand: Report of a WHO expert consultation. Vaccine, 55, 127008. https://doi.org/10.1016/j.vaccine.2025.127008

Fousseni, S., Ngangue, P., Barro, A., Ramde, S. W., Bihina, L. T., Ngoufack, M. N., Bayoulou, S., Kiki, G. M., & Salfo, O. (2025). Navigating the Road to Immunization Equity: Systematic Review of Challenges in Introducing New Vaccines into Sub-Saharan Africa’s Health Systems. Vaccines, 13(3), 269.ttps://doi.org/10.3390/vaccines13030269

Gloeck, N. R., Leong, T. D., Mthethwa, M., Iwu-Jaja, C. J., Katoto, P. D., Wiysonge, C. S., & Kredo, T. (2025). Typhoid conjugate vaccines for preventing typhoid fever (enteric fever). The Cochrane Database of Systematic Reviews, 2025(5), CD015746. oi: 10.1002/14651858.CD015746.pub2

Iwu-Jaja, C., Gahimbare, L., Mazingisa, A. V., Fuller, W., Mazengiya, D. Y., Okeibunor, J., Olu, O. O., Katoto, P. de M. C., Yahaya, A. A., & Nyarko, K. (2025). Mapping the role of vaccines in combating AMR in the WHO African region: A scoping review and implications for research and policy. BMC Infectious Diseases, 25(1), 1–11.https://doi.org/10.1186/s12879-025-11080-5

Jamil, H., Nohri, A. R., Sama, G., Malik, N. A., & Naveed, S. (2025). KNOWLEDGE, ATTITUDES, AND PRACTICES TOWARDS MULTIDRUG-RESISTANT TYPHOID IN PEDIATRIC POPULATION IN PAKISTAN. Insights-Journal of Life and Social Sciences, 3(3 (Social)), 7–16. https://doi.org/10.71000/6297gj91

Kamanzi Ntakirutimana, G. (n.d.). Economic and Health System Impacts of Typhoid Control Strategies in Uganda: Vaccination Versus Antibiotic Treatmenthttp://hdl.handle.net/20.500.12306/12825

Lucero, Y. C., Velarde, J. J., & O’Ryan, M. L. (2025). Microorganisms responsible for neonatal diarrhea. In Remington and Klein’s Infectious Diseases of the Fetus and Newborn Infant (pp. 310-347. e14). Elsevier. https://doi.org/10.1016/B978-0-323-79525-8.00021-4

Pinto, M., Durante, S., Carducci, M., Massai, L., Alfini, R., Mylona, E., Karkey, A., Baker, S., Micoli, F., & Giannelli, C. (2025). The Salmonella Paratyphi A O-Antigen Glycoconjugate Vaccine Is Able to Induce Antibodies with Bactericidal Activity Against a Panel of Clinical Isolates. Vaccines, 13(2), 122. https://doi.org/10.3390/vaccines13020122

Sirajee, A. S., & Ahsan, S. (2025). Design of a cross-protective multi-epitope vaccine targeting the most prevalent typhoidal and non-typhoidal Salmonella serovars. Heliyon, 11(5). https://doi.org/10.1016/j.heliyon.2025.e42954

Wawrzuta, D., Giefert, S., & Klejdysz, J. (2025). Optimizing immunization in pediatric oncology: Development and evaluation of an automated scheduling tool. International Journal of Medical Informatics, 105950. https://doi.org/10.1016/j.ijmedinf.2025.105950