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NISH (NITAG Support Hub) 2: Covid-19 vaccine hesitancy/confidence in Africa

This Library Guide contains published and unpublished information on vaccine hesitancy and related issues in the context of COVID-19 vaccination in Subsaharan Africa

Pubmed : COVID-19 vaccine hesitancy AND Congo/Democratic Republic of Congo/DRC

Bateyi Mustafa, S.H., Kabamba, M. and Onyango, R.O., 2023. Determinants of parents’ intention to vaccinate their children aged 12–17 years against COVID-19 in North Kivu (Democratic Republic of Congo). Human Vaccines & Immunotherapeutics19(1), p.2179788.
Lees, S., Enria, L. and James, M., 2023. Contesting the crisis narrative: epidemic accounts in Sierra Leone, Tanzania, and Democratic Republic of the Congo. Disasters.
Munyeku-Bazitama, Y., Folefack, G.T., Yambayamba, M.K., Tshiminyi, P.M., Kazenza, B.M., Otshudiema, J.O., Guinko, N.T., Umba, M.D., Mulumba, A., Baketana, L.K. and Mukadi, P.K., 2023. High SARS-CoV-2 Seroprevalence after Second COVID-19 Wave (October 2020–April 2021), Democratic Republic of the Congo. Emerging Infectious Diseases, 29(1), pp.89-97.
de Figueiredo, A., Simas, C. and Larson, H.J., 2022. COVID-19 vaccine acceptance and its socio-demographic and emotional determinants: A multi-country cross-sectional study (including Congo). Vaccine.
Davis TP Jr, Yimam AK, Kalam MA, Tolossa AD, Kanwagi R, Bauler S, Kulathungam L, Larson H. Behavioural Determinants of COVID-19-Vaccine Acceptance in Rural Areas of Six Lower- and Middle-Income Countries. Vaccines (Basel). 2022 Jan 29;10(2):214. doi: 10.3390/vaccines10020214.
Shakeel CS, Mujeeb AA, Mirza MS, Chaudhry B, Khan SJ. Global COVID-19 Vaccine Acceptance: A Systematic Review of Associated Social and Behavioral Factors. Vaccines (Basel). 2022 Jan 12;10(1):110. doi: 10.3390/vaccines10010110. PMID:
Mutombo PN, Fallah MP, Munodawafa D, Kabel A, Houeto D, Goronga T, Mweemba O, Balance G, Onya H, Kamba RS, Chipimo M, Kayembe JN, Akanmori B. COVID-19 vaccine hesitancy in Africa: a call to action. Lancet Global Health. 2022 Mar;10(3):e320-e321. doi: 10.1016/S2214-109X(21)00563-5
Anjorin AA, Odetokun IA, Abioye AI, Elnadi H, Umoren MV, Damaris BF, Eyedo J, Umar HI, Nyandwi JB, Abdalla MM, Tijani SO, Awiagah KS, Idowu GA, Fabrice SNA, Maisara AMO, Razouqi Y, Mhgoob ZE, Parker S, Asowata OE, Adesanya IO, Obara MA, Jaumdally S, Kitema GF, Okuneye TA, Mbanzulu KM, Daitoni H, Hallie EF, Mosbah R, Fasina FO. Will Africans take COVID-19 vaccination? PLoS One. 2021 Dec 1;16(12):e0260575. doi: 10.1371/journal.pone.0260575
Sturmberg J, Paul E, Van Damme W, Ridde V, Brown GW, Kalk A. The danger of the single storyline obfuscating the complexities of managing SARS-CoV-2/COVID-19. Journal of Evaluation in Clinical Practice. 2021 Nov 25. doi: 10.1111/jep.13640. Epub ahead of print.
Wake AD. The Willingness to Receive COVID-19 Vaccine and Its Associated Factors: "Vaccination Refusal Could Prolong the War of This Pandemic" - A Systematic Review. Risk Management and Healthcare Policy 2021 Jun 21;14:2609-2623. doi: 10.2147/RMHP.S311074
Otu, A., Osifo-Dawodu, E., Atuhebwe, P., Agogo, E. and Ebenso, B., 2021. Beyond vaccine hesitancy: time for Africa to expand vaccine manufacturing capacity amidst growing COVID-19 vaccine nationalism. The Lancet Microbe, 2(8), pp.e347-e348.
Wirsiy FS, Nkfusai CN, Ako-Arrey DE, Dongmo EK, Manjong FT, Cumber SN. Acceptability of COVID-19 Vaccine in Africa. Global Health and Education Projects International Journal of Maternal and Child Health (MCH) and AIDS (IJMA)2021;10(1):134-138. doi: 10.21106/ijma.482.
Sallam M. COVID-19 Vaccine Hesitancy Worldwide: A Concise Systematic Review of Vaccine Acceptance Rates. Vaccines (Basel). 2021 Feb 16;9(2):160. doi: 10.3390/vaccines9020160.
Shachar C, Reiss DR. When Are Vaccine Mandates Appropriate?AMA Journal of Ethics 2020 Jan 1;22(1):E36-42. doi: 10.1001/amajethics.2020.36. (Not OA)
Ditekemena, J.D., Nkamba, D.M., Mavoko, A.M., Hypolite, M., Siewe Fodjo, J.N., Luhata, C., Obimpeh, M., Van Hees, S., Nachega, J.B. and Colebunders, R., 2021. COVID-19 vaccine acceptance in the Democratic Republic of Congo: a cross-sectional survey. Vaccines, 9(2), p.153.

Nzaji, M.K., Ngombe, L.K., Mwamba, G.N., Ndala, D.B.B., Miema, J.M., Lungoyo, C.L., Mwimba, B.L., Bene, A.C.M. and Musenga, E.M., 2020. Acceptability of vaccination against COVID-19 among healthcare workers in the Democratic Republic of the Congo. Pragmatic and observational research, 11, p.103. (Not OA)

Bono, S.A., Faria de Moura Villela, E., Siau, C.S., Chen, W.S., Pengpid, S., Hasan, M.T., Sessou, P., Ditekemena, J.D., Amodan, B.O., Hosseinipour, M.C. and Dolo, H., 2021. Factors affecting COVID-19 vaccine acceptance: an international survey among low-and middle-income countries. Vaccines, 9(5), p.515.

Wake, A.D., 2021. The willingness to receive COVID-19 vaccine and its associated factors:“vaccination refusal could prolong the war of this pandemic”–a systematic review. Risk management and healthcare policy, 14, p.2609.

Sallam M, Al-Sanafi M, Sallam M. A Global Map of COVID-19 Vaccine Acceptance Rates per Country: An Updated Concise Narrative Review. Journal of Multidisciplinary Healthcare. 2022 Jan 11;15:21-45. doi: 10.2147/JMDH.S347669


Mangla S, Zohra Makkia FT, Pathak AK, Robinson R, Sultana N, Koonisetty KS, Karamehic-Muratovic A, Nguyen UDT, Rodriguez-Morales AJ, Sanchez-Duque JA, Zamba PT, Aghamohammadi N, Cs F, Haque U. COVID-19 Vaccine Hesitancy and Emerging Variants: Evidence from Six Countries. Behavioral Sciences (Basel). 2021 Oct 28;11(11):148. doi: 10.3390/bs11110148



Croke, K., Coville, A., Mvukiyehe, E., Dohou, C.J., Zibika, J.P., Ghib, L.S., Andreottola, M., Bokasola, Y.L. and Quattrochi, J.P., 2022. Effects of a community‐driven water, sanitation, and hygiene programme on COVID‐19 symptoms, vaccine acceptance and non‐COVID illnesses: A cluster‐randomised controlled trial in rural Democratic Republic of Congo. Tropical Medicine & International Health. (Not OA)


The government of the Democratic Republic of Congo (DRC) responded to COVID-19 with policy measures, such as business and school closures and distribution of vaccines, which rely on citizen compliance. In other settings, prior experience with effective government programmes has increased compliance with public health measures. We study the effect of a national water, sanitation, and hygiene programme on compliance with COVID-19 policies.

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Garbern, S.C., Perera, S.M., Mbong, E.N., Kulkarni, S., Fleming, M.K., Ombeni, A.B., Muhayangabo, R.F., Tchoualeu, D.D., Kallay, R., Song, E. and Powell, J., 2023. COVID-19 Vaccine Perceptions among Ebola-Affected Communities in North Kivu, Democratic Republic of the Congo, 2021. Vaccines11(5), p.973.
Wiysonge, C.S., Ndwandwe, D., Ryan, J., Jaca, A., Batouré, O., Anya, B.P.M. and Cooper, S., 2022. Vaccine hesitancy in the era of COVID-19: could lessons from the past help in divining the future?. Human vaccines & immunotherapeutics, 18(1), pp.1-3.
Machingaidze, S. and Wiysonge, C.S., 2021. Understanding COVID-19 vaccine hesitancy. Nature Medicine, 27(8), pp.1338-1339. (Not OA).
Wilson, S.L. and Wiysonge, C., 2020. Social media and vaccine hesitancy. BMJ global health, 5(10), p.e004206.
Simas, C. and Larson, H.J., 2021. Overcoming vaccine hesitancy in low-income and middle-income regions. Nature Reviews Disease Primers, 7(1), pp.1-2. (Not OA)
Salomoni, M.G., Di Valerio, Z., Gabrielli, E., Montalti, M., Tedesco, D., Guaraldi, F. and Gori, D., 2021. Hesitant or not hesitant? A systematic review on global COVID-19 vaccine acceptance in different populations. Vaccines, 9(8), p.873.
Amuzie, C.I., Odini, F., Kalu, K.U., Izuka, M., Nwamoh, U., Emma-Ukaegbu, U. and Onyike, G., 2021. COVID-19 vaccine hesitancy among healthcare workers and its socio-demographic determinants in Abia State, Southeastern Nigeria: a cross-sectional study. The Pan African Medical Journal, 40.
Africa, C.D.C., 2021. COVID 19 vaccine perceptions: a 15 country study.
Sallam, M., Al-Sanafi, M. and Sallam, M., 2022. A global map of COVID-19 vaccine acceptance rates per country: an updated concise narrative review. Journal of Multidisciplinary Healthcare, 15, p.21.

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