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NISH (NITAG Support Hub) 2: Covid-19 vaccine hesitancy/confidence in Africa

This Library Guide contains published and unpublished information on vaccine hesitancy and related issues in the context of COVID-19 vaccination in Subsaharan Africa

Pubmed : Covid-19 AND "vaccination hesitancy" AND Kenya

Ireri, E.M., Mutugi, M.W., Falisse, J.B., Mwitari, J.M. and Atambo, L.K., 2023. Influence of conspiracy theories and distrust of community health volunteers on adherence to COVID-19 guidelines and vaccine uptake in Kenya. PLOS global public health3(3), p.e0001146.
Yego, J., Korom, R., Eriksson, E., Njavika, S., Sane, O., Kanorio, P., Rotich, O., Wambui, S. and Mureithi, E., 2023. A Comparison of Strategies to Improve Uptake of COVID-19 Vaccine among High-Risk Adults in Nairobi, Kenya in 2022. Vaccines11(2), p.209.
Essoh, T.A., Adeyanju, G.C., Adamu, A.A., Tall, H., Aplogan, A. and Tabu, C., 2023. Exploring the factors contributing to low vaccination uptake for nationally recommended routine childhood and adolescent vaccines in Kenya. BMC Public Health23(1), pp.1-10.
Marwa, M.M., Kinuthia, J., Larsen, A., Dettinger, J.C., Gomez, L.A., Awino, P., Abuna, F., Watoyi, S., Ochieng, B., Ngumbau, N. and John‐Stewart, G., 2023. COVID‐19 vaccine hesitancy among pregnant and postpartum Kenyan women. International Journal of Gynecology & Obstetrics.
(Not OA)
Rego, R.T., Kenney, B., Ngugi, A.K., Espira, L., Orwa, J., Siwo, G.H., Sefa, C., Shah, J., Weinheimer-Haus, E., Delius, A.J.S. and Pape, U.J., 2023. COVID-19 vaccination refusal trends in Kenya over 2021. Vaccine41(5), pp.1161-1168. (Not OA)
Boi‐Dsane, N.A., Dzudzor, B., Alhassan, Y. and Aheto, J.M., 2023. Prevalence of common adverse events experienced following COVID‐19 vaccination and its associated factors in Ghana: Cross‐sectional study design. Health Science Reports, 6(1), p.e1012.
Rego, R.T., Kenney, B., Ngugi, A.K., Espira, L., Orwa, J., Siwo, G.H., Sefa, C., Shah, J., Weinheimer-Haus, E., Mphil, A.J.S.D. and Pape, U.J., 2023. COVID-19 vaccination refusal trends in Kenya over 2021. Vaccine.
Abstract: Background Vaccination refusal exacerbates global COVID-19 vaccination inequities. No studies in East Africa have examined temporal trends in vaccination refusal, precluding addressing refusal. We assessed vaccine refusal over time in Kenya, and characterized
factors associated with changes in vaccination refusal. Methods We analyzed data from the Kenya Rapid Response Phone Survey (RRPS), a household cohort survey representative of the Kenyan population including refugees. Vaccination refusal (defined as the respondent …
Lazarus, J.V., Wyka, K., White, T.M., Picchio, C.A., Gostin, L.O., Larson, H.J., Rabin, K., Ratzan, S.C., Kamarulzaman, A. and El-Mohandes, A., 2023. A survey of COVID-19 vaccine acceptance across 23 countries in 2022. Nature Medicine, pp.1-10.
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continued to mutate and
spread in 2022 despite the introduction of safe, effective vaccines and medications. Vaccine hesitancy remains substantial, fueled in part by misinformation. Our third study of Coronavirus Disease 2019 (COVID-19) vaccine hesitancy among 23,000 respondents in 23
countries (Brazil, Canada, China, Ecuador, France, Germany, Ghana, India, Italy, Kenya, Mexico, Nigeria, Peru, Poland, Russia, Singapore, South Africa, South Korea, Spain ...
Zavala, E., Fesshaye, B., Lee, C., Mutwiwa, S., Njagi, W., Munyao, P., Njogu, R., Gur-Arie, R., Paul, A.M., Holroyd, T.A. and Singh, P., 2022. Lack of clear national policy guidance on COVID-19 vaccines influences behaviors in pregnant and lactating women in Kenya. Human Vaccines & Immunotherapeutics, p.2127561.
Rego, R.T., Ngugi, A.K., Sophie Delius, A.J., Luchters, S., Kolars, J.C., Irfan, F.B., Weinheimer-Haus, E., Abubakar, A., Shah, R., Zhu, J. and Boulton, M.L., 2022. COVID-19 vaccine hesitancy among non-refugees and refugees in Kenya. PLOS Global Public Health2(8), p.e0000917.

Davis Jr, T.P., Yimam, A.K., Kalam, M.A., Tolossa, A.D., Kanwagi, R., Bauler, S., Kulathungam, L. and Larson, H., 2022. Behavioural determinants of COVID-19-vaccine acceptance in rural areas of six lower-and middle-income countries. Vaccines, 10(2), p.214.
Limaye, R.J., Paul, A., Gur-Arie, R., Zavala, E., Lee, C., Fesshaye, B., Singh, P., Njagi, W., Odila, P., Munyao, P. and Njogu, R., 2022. A socio-ecological exploration to identify factors influencing the COVID-19 vaccine decision-making process among pregnant and lactating women: Findings from Kenya. Vaccine.
Wanyonyi, C.N., Audi, A., Oduor, C., Ombok, C., Oketch, D., Aol, G., Ouma, A., Osoro, E.M., Ngere, I., Njoroge, R. and Munyua, P.M., 2022. COVID-19 Knowledge, Attitudes and Practices and Vaccine Acceptability in Rural Western Kenya and an Urban Informal Settlement in Nairobi, Kenya, May 2021: A Cross-sectional Survey. (Pre-print)
Maina, R., Kimani, R.W., Orwa, J., Mutwiri, B.D., Nyariki, C.K., Shaibu, S. and Fleming, V., 2022. Knowledge, Attitudes, and Preparedness for Managing Pregnant and Postpartum Women with COVID-19 Among Nurse-Midwives in Kenya. SAGE Open Nursing, 8, p.23779608221106445.


Oyekale AS. Compliance Indicators of COVID-19 Prevention and Vaccines Hesitancy in Kenya: A Random-Effects Endogenous Probit Model. Vaccines (Basel). 2021 Nov 19;9(11):1359. doi: 10.3390/vaccines9111359

Orangi S, Pinchoff J, Mwanga D, Abuya T, Hamaluba M, Warimwe G, Austrian K, Barasa E. Assessing the Level and Determinants of COVID-19 Vaccine Confidence in Kenya. Vaccines (Basel). 2021 Aug 23;9(8):936. doi: 10.3390/vaccines9080936

Carpio, C.E., Sarasty, O., Hudson, D., Macharia, A. and Shibia, M., 2021. The demand for a COVID-19 vaccine in Kenya. Human Vaccines & Immunotherapeutics, 17(10), pp.3463-3471. (Not OA)
Davis, R., 2021. Vaccine hesitancy and other obstacles to COVID-19 control: lessons from smallpox. The Pan African Medical Journal, 40.


Cochrane Library

COVID-19 vaccine messaging on social media in Kenya, Nepal, and the Philippines


Google Scholar

Alam, A., Khan, A., Imam, N., Siddiqui, M.F., Waseem, M., Malik, M.Z. and Ishrat, R., 2020. Design of an epitope-based peptide vaccine against the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2): a vaccine-informatics approach. BioRxiv. (Preprint - not peer-reviewed)
Galdiero, M., Galdiero, M., Folliero, V., Zannella, C., De Filippis, A., Mali, A., Rinaldi, L. and Franci, G., 2021. SARS-CoV-2 vaccine development: Where are we. European Review for Medical and Pharmacological Sciences, 25(6), pp.2752-84.
Onovo, A.A., Atobatele, A., Kalaiwo, A., Obanubi, C., James, E., Gado, P., Odezugo, G., Ogundehin, D., Magaji, D. and Russell, M., 2020. Using supervised machine learning and empirical Bayesian kriging to reveal correlates and patterns of COVID-19 disease outbreak in sub-Saharan Africa: exploratory data analysis. medRxiv. (Preview - not peer-reviewed)

WHO Afro

Africa-Wide Information

Limaye, R.J., Balgobin, K., Michel, A., Schulz, G. and Erchick, D.J., 2022. What message appeal and messenger are most persuasive for COVID-19 vaccine uptake: Results from a 5-country survey in India, Indonesia, Kenya, Nigeria, and Ukraine. PloS one, 17(9), p.e0274966.
Naqvi, S., Saleem, S., Naqvi, F., Billah, S.M., Nielsen, E., Fogleman, E., Peres‐da‐Silva, N., Figueroa, L., Mazariegos, M., Garces, A.L. and Patel, A., 2022. Knowledge, attitudes, and practices of pregnant women regarding COVID‐19 vaccination in pregnancy in 7 low and middle‐income countries: An observational trial from the Global Network. BJOG: An International Journal of Obstetrics & Gynaecology. (Not OA)
Nivedita, K. and Shanthini, F.N., 2016. Knowledge, attitude and practices of pregnant women regarding anemia, iron rich diet and iron supplements and its impact on their hemoglobin levels. Int J Reprod Contracept Obstet Gynecol, 5(2), pp.425-31. (Not OA)