Skip to Main Content

NISH (NITAG Support Hub) 4: HPV OR Human Papillomavirus Vaccines: Systematic Reviews on the HPV vaccines

This Library Guide is a collection of useful documents & evidence on the efficacy, effectiveness and impact of the HPV OR Papillomavirus vaccine to support NITAG members and other policy makers throughout Africa with making evidence-based recommendations

Systematic Reviews

NEW !!
Han, J., Zhang, L., Chen, Y., Zhang, Y., Wang, L., Cai, R., Li, M., Dai, Y., Dang, L., Chen, H., & Zhu, L. (2025). Global HPV vaccination programs and coverage rates: a systematic review. EClinicalMedicine, 84, 103290. hhttps://doi.org/10.1016/j.eclinm.2025.103290

Alshamrani, M. M., El-Saed, A., Al-Fayez, S., Ameer, K., Al Zunitan, M., Abalkhail, M., ... & Baller, A. (2025). Routes of transmission of mpox by virus clade and geographic distribution: A systematic review. Journal of Infection and Public Health, 102985. https://doi.org/10.1016/j.jiph.2025.102985
 

Wang, M., Tian, X., Zeng, Y., Yue, Y., Zhu, Z., Li, Z., ... & Sun, Y. (2025). International prevalence and associated factors of parental vaccine hesitancy in human papillomavirus vaccination: A systematic review and meta-analysis. International Journal of Nursing Studies, 105239. https://doi.org/10.1016/j.ijnurstu.2025.105239

Chee, C. S. M., Tan, S. S. N., Voon, P. J., Augustin, Y., Krishna, S., Mat Ali, N., Wan Maharuddin, I. B., Tiong, X. T., Abdul Rahim, N. K. B., Ismail, A. M., Sim, E. U., Divis, P. C., Jinam, T. A., & Lim, M. S. H. (2025). Human papillomavirus (HPV) genotype distribution in Malaysia: A systematic review. BMC infectious diseases, 25(1), 1010. https://doi.org/10.1186/s12879-025-11441-0

Gebreal, A., Ashmawy, R., Ahmed, M. J., Khattab, M., Shata, K. S., Elmansoury, A., ... & Ghazy, R. M. (2025). A systematic review and meta-analysis on parental uptake and willingness to vaccinate children against human papillomavirus in the Eastern Mediterranean Region. Vaccine, 126832. https://doi.org/10.1016/j.vaccine.2025.126832

Iwami, M., Bouaddi, O., Razai, M. S., Mansour, R., Morais, B., Ali, N. M., ... & Hargreaves, S. (2025). Defining drivers of human papillomavirus (HPV) vaccine uptake in migrant populations globally and strategies and interventions to improve coverage: a systematic review. medRxiv, 2025-01. https://doi.org/10.1101/2025.01.31.25321303

Olaoye, O., & Macdonald, S. (2024). A systematic review of interventions to promote human papillomavirus (HPV) vaccination in Africa. Public Health, 234, 47–57. https://doi.org/10.1016/j.puhe.2024.05.015

Perlman, S., Wamai, R.G., Bain, P.A., Welty, T., Welty, E. and Ogembo, J.G., 2014. Knowledge and awareness of HPV vaccine and acceptability to vaccinate in sub-Saharan Africa: a systematic review. PloS one, 9(3), p.e90912. doi.org/10.1371/journal.pone.0090912

 Whitworth, H. S., Mounier-Jack, S., Choi, E. M., Gallagher, K. E., Howard, N., Kelly, H., Mbwanji, G., Kreimer, A. R., Basu, P., Barnabas, R., Drolet, M., Brisson, M., & Watson-Jones, D. (2024). Efficacy and immunogenicity of a single dose of human papillomavirus vaccine compared to multidose vaccination regimens or no vaccination: An updated systematic review of evidence from clinical trials. Vaccine: X, 19, 100486. https://doi.org/10.1016/j.jvacx.2024.100486   DOI: 10.1016/j.jvacx.2024.100486

Whitworth, H. S., Mounier-Jack, S., Choi, E. M., Gallagher, K. E., Howard, N., Kelly, H., Mbwanji, G., Kreimer, A. R., Basu, P., Barnabas, R., Drolet, M., Brisson, M., & Watson-Jones, D. (2024). Efficacy and immunogenicity of a single dose of human papillomavirus vaccine compared to multidose vaccination regimens or no vaccination: An updated systematic review of evidence from clinical trials. Vaccine: X, 19, 100486. https://doi.org/10.1016/j.jvacx.2024.100486

Zewdie, A., Kasahun, A.W., Adane, H.A. and Mose, A., 2023. Willingness to vaccinate their daughters against human papillomavirus among parents of Ethiopian adolescent girls: a systematic review and meta-analysis. Journal of Pharmaceutical Policy and Practice, 16(1), p.126.  DOI: 10.1186/s40545-023-00639-9

Addisu, D., Gebeyehu, N.A. and Belachew, Y.Y., 2023. Knowledge, attitude, and uptake of human papillomavirus vaccine among adolescent schoolgirls in Ethiopia: a systematic review and meta-analysis. BMC Women's Health, 23(1), pp.1-12. DOI: 10.1186/s12905-023-02412-1

Oketch, S.Y., Ochomo, E.O., Orwa, J.A., Mayieka, L.M. and Abdullahi, L.H., 2023. Communication strategies to improve human papillomavirus (HPV) immunisation uptake among adolescents in sub-Saharan Africa: a systematic review and meta-analysis. BMJ open, 13(4), p.e067164. DOI: 10.1136/bmjopen-2022-067164

Iskandar, R., Taghavi, K., Low, N., Bramer, W.M., Egger, M. and Rohner, E., 2022. Mathematical Models for Evaluating Effectiveness and Cost-Effectiveness of Cervical Cancer Control Policies in Populations Including Women Living With Human Immunodeficiency Virus: A Scoping Review. Value in health regional issues, 32, pp.39-46. (NOT OA)

Kutz, J.M., Rausche, P., Gheit, T., Puradiredja, D.I. and Fusco, D., 2023. Barriers and facilitators of HPV vaccination in sub-saharan Africa: a systematic review. BMC Public Health, 23(1), p.974. doi: 10.1186/s12889-023-15842-1

Makadzange, E.E., Peeters, A., Joore, M.A. and Kimman, M.L., 2022. The effectiveness of health education interventions on cervical cancer prevention in Africa: A systematic review. Preventive Medicine, p.107219. (NOT OA)

Zibako, P., Hlongwa, M., Tsikai, N., Manyame, S. and Ginindza, T.G., 2022. Mapping Evidence on Management of Cervical Cancer in Sub-Saharan Africa: Scoping Review. International Journal of Environmental Research and Public Health, 19(15), p.9207. (NOT OA)

Asangbeh-Kerman, S.L., Davidović, M., Taghavi, K., Kachingwe, J., Rammipi, K.M., Muzingwani, L., Pascoe, M., Jousse, M., Mulongo, M., Mwanahamuntu, M. and Tapela, N., 2022. Cervical cancer prevention in countries with the highest HIV prevalence: a review of policies. BMC public health, 22(1), pp.1-12. DOI: 10.1186/s12889-022-13827-0

Wirtz, C., Mohamed, Y., Engel, D., Sidibe, A., Holloway, M., Bloem, P., Kumar, S., Brotherton, J., Reis, V. and Morgan, C., 2022. Integrating HPV vaccination programs with enhanced cervical cancer screening and treatment, a systematic review. Vaccine, 40, pp.A116-A123.  DOI: 10.1016/j.vaccine.2021.11.013

Wilson, R., 2021. HPV vaccine acceptance in West Africa: a systematic literature review. Vaccine, 39(37), pp.5277-5284. (NOT OA)