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NISH (NITAG Support Hub) 12: Whole-cell (wP) Hexavalent vaccine: Domain 2 : Benefit and Harms

This Library Guide is a collection of useful documents & evidence on the safety, efficacy, effectiveness and impact of the whole-cell (wP) Hexavalent vaccine to support NITAG members and other policy makers throughout Africa with making evidence-based r

Keywords used

Whole Cell (wP) Hexavalent vaccine and “benefits and harms” OR safety OR efficacy OR effectiveness OR “adverse events”

Retrieved from Google Scholar

Adams, R. M., & Gonik, B. (2024). The Evolving Maternal Vaccine Platform. Reproductive Medicine, 5(3), 154–171. https://doi.org/10.3390/reprodmed5030014

Alghounaim, M., Alsaffar, Z., Alfraij, A., Bin-Hasan, S., & Hussain, E. (2022). Whole-cell and acellular pertussis vaccine: reflections on efficacy. Medical Principles and Practice31(4), 313-321. https://doi.org/10.1159/000525468

Banda, G., Mugwagwa, J., Mackintosh, M., & Mkwashi, A. (2022). The Localisation of Medical Manufacturing in Africa. URL: https://www.iej.org.za/localisation-of-medical-man...

Jansen, M. C. (2022). The relationship between the nutritional status of children within early childhood development centres in delft and their compliance to the expanded programme of immunization and routine vitamin a supplementation. [Dissertation] ttps://hdl.handle.net/10566/11195

Kana, B. D., Arbuthnot, P., Botwe, B. K., Choonara, Y. E., Hassan, F., Louzir, H., Matsoso, P., Moore, P. L., Muhairwe, A., & Naidoo, K. (2023). Opportunities and challenges of leveraging COVID-19 vaccine innovation and technologies for developing sustainable vaccine manufacturing capabilities in Africa. The Lancet Infectious Diseases, 23(8), e288–e300. https://www.thelancet.com/action/showPdf?pii=S1473-3099%2822%2900878-7

Kour, I., Singhal, L., & Gupta, V. (2023). Diphtheria: A paradigmatic vaccine-preventable toxigenic disease with changing epidemiology. In Recent Advances in Pharmaceutical Innovation and Research (pp. 749–759). Springer.

Madhi, S. A., Mitha, I., Cutland, C., Groome, M., & Santos-Lima, E. (2011). Immunogenicity and safety of an investigational fully liquid hexavalent combination vaccine versus licensed combination vaccines at 6, 10, and 14 weeks of age in healthy South African infants. The Pediatric Infectious Disease Journal30(4), e68-e74. Open here

Nnaji, C. (2024). Assessing and addressing missed opportunities for vaccination in Cape Town through a collaborative quality improvement approach. [Dissertation] http://hdl.handle.net/11427/40377

Nnaji, C. A., Wiysonge, C. S., Adamu, A. A., Lesosky, M., Mahomed, H., & Ndwandwe, D. (2022). Missed opportunities for vaccination and associated factors among children attending primary health care facilities in Cape Town, South Africa: A pre-intervention multilevel analysis. Vaccines, 10(5), 785. https://doi.org/10.3390/vaccines10050785

Pilusa, T. D. (2021). Prevalence and determinants of childhood vaccination coverage at selected primary health care facilities, Bushbuckridge Sub-District, Mpumalanga Province, South Africa. [Dissertation] http://hdl.handle.net/10386/3616

Sadarangani, M., Kollmann, T., Bjornson, G., Heath, P., Clarke, E., Marchant, A., Levy, O., Leuridan, E., Ulloa-Gutierrez, R., & Cutland, C. L. (2021). The Fifth International Neonatal and Maternal Immunization Symposium (INMIS 2019): Securing protection for the next generation. Msphere, 6(1), 10.1128/msphere. 00862-20. https://doi.org/10.1128/msphere.00862-20

Saso, A., Roetynck, S., Okoye, M., Kanteh, E., Kumado, M., Roberts, E., Faal, A., Jobe, H., Jeffries, D., & Kelly, D. (2024). The impact of acellular pertussis vaccination in pregnancy on the immunogenicity of acellular versus whole-cell pertussis vaccines in infancy: A protocol for a phase IV randomised, controlled mother-infant pertussis vaccine trial (The Gambian Pertussis Study, GaPs). Wellcome Open Research, 9, 487. [Protocol] https://wellcomeopenresearch.org/articles/9-487

Szwejser-Zawislak, E., Wilk, M. M., Piszczek, P., Krawczyk, J., WilczyƄska, D., & Hozbor, D. (2022). Evaluation of whole-cell and acellular pertussis vaccines in the context of long-term herd immunity. Vaccines11(1), 1. https://doi.org/10.3390/vaccines11010001

von Hunolstein, C., Schofield, T., Sloots, A., Gairola, S., Riyanti, I., Resnawati, E., ... & Sharma, S. (2024). POTENCY TESTING OF WHOLE-CELL PERTUSSIS-CONTAINING VACCINES: RESULTS OF MULTILABORATORY ASSESSMENT OF THE PERTUSSIS SEROLOGICAL POTENCY TEST. WHO Drug Information38(4). (NOT OA)