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NISH (NITAG Support Hub) 14: Pentavalent Meningococcal ACWYX Conjugate Vaccine: Africa

Africa

 

Karachaliou Prasinou, A., & Trotter, C. (2025). Modelling of strategies for the introduction and routine use of multivalent meningococcal conjugate vaccines (MMCVs) in the African meningitis belt. PloS one, 20(8), e0330627. https://doi.org/10.1371/journal.pone.0330627

Diallo, F., Haidara, F. C., Tapia, M. D., Islas, C. P. D., Alderson, M. R., Hausdorff, W. P., ... & Chen, W. H. (2025). Safety and immunogenicity of a pentavalent meningococcal conjugate vaccine targeting serogroups A, C, W, Y, and X when co-administered with routine childhood vaccines at ages 9 months and 15 months in Mali: A single-centre, double-blind, randomised, controlled, phase 3, non-inferiority trial. The Lancet, 405(10484), 1069-1080. https://doi.org/10.1016/S0140-6736(25)00046-7

 Martinón-Torres, F., Simko, R., Ebert, R., Rämet, M., Zocchetti, C., Syrkina, O., ... & Bertrand-Gerentes, I. (2025). Five-Year immune persistence of a quadrivalent meningococcal conjugate vaccine (MenACYW-TT) and immunogenicity and safety of a booster dose in children. Infectious Diseases and Therapy, 1-20. https://doi.org/10.1007/s40121-025-01121-6

Collins JP, Crowe SJ, Ortega-Sanchez IR, et al. (2024). Use of the Pfizer Pentavalent Meningococcal Vaccine Among Persons Aged ≥10 Years: Recommendations of the Advisory Committee on Immunization Practices ― United States, 2023. MMWR: Morbidity and Mortality Weekly Report, 73(15), 345-350.
https://doi.org/10.15585/mmwr.mm7315a4


Dhraief, S., Meftah, K., Mhimdi, S., Khiari, H., Aloui, F., Borgi, A., ... & Smaoui, H. (2024). Epidemiological and bacterial profile of childhood meningitis in Tunisia. Acta Microbiologica et Immunologica Hungarica, 71(2), 148-154.  https://doi.org/10.1556/030.2024.02208

Sharma, P., Kale, S., Phugare, S., Goel, S. K., & Gairola, S. (2024). Analytical challenges in novel pentavalent meningococcal conjugate vaccine (A, C, Y, W, X). Vaccines, 12(11), 1227.
https://doi.org/10.3390/vaccines12111227


Sharma, P., Kale, S., Phugare, S., Pendharkar, S., Shinde, P., Mandhan, A., ... & Gairola, S. (2024). Molecular size distribution in pentavalent (A, C, Y, W, X) meningococcal polysaccharide conjugate vaccine by HPSEC-UV-MALS-RI method-a conceivable stability indicating parameter. Journal of Chromatography B, 1236, 124048. https://doi.org/10.1016/j.jchromb.2024.124048

Ukoaka, B. M., Okesanya, O. J., Daniel, F. M., Affia, M. O., & Emeruwa, V. E. (2024). A perspective on the novel pentavalent Men5CV (NmCV-5) meningitis vaccine and Nigeria’s pioneering rollout campaign. Le Infezioni in Medicina, 32(3), 323-9. https://pubmed.ncbi.nlm.nih.gov/39282539

Yonts, A. B., Gaviria-Agudelo, C., Kimberlin, D. W., O’Leary, S. T., & Paulsen, G. C. (2024). Fall 2023 ACIP Update on Meningococcal, RSV, COVID-19, and other Pediatric vaccines. Pediatrics,153(3), e2023064990. https://doi.org/10.1542/peds.2023-064990

Haidara, F. C., Umesi, A., Sow, S. O., Ochoge, M., Diallo, F., Imam, A., ... & Clarke, E. (2023). Meningococcal ACWYX conjugate vaccine in 2-to-29-year-olds in Mali and Gambia. New England Journal of Medicine, 388(21), 1942-1955. https://www.nejm.org/doi/full/10.1056/NEJMoa2214924

Alderson, M. R., Arkwright, P. D., Bai, X., Black, S., Borrow, R., Caugant, D. A., ... & Zhu, B. (2022). Surveillance and control of meningococcal disease in the COVID-19 era: A global meningococcal initiative review. Journal of Infection, 84(3), 289-296.
https://doi.org/10.1016/j.jinf.2021.11.016

Katz, S., Townsend-Payne, K., Louth, J., Lee-Jones, L., Trotter, C., Dano, I. D., ... & MenAfriCar Consortium. (2022). Validation and use of a serum bactericidal antibody assay for Neisseria meningitidis serogroup X in a seroprevalence study in Niger, West Africa. Vaccine, 40(42), 6042-6047. https://doi.org/10.1016/j.vaccine.2022.08.013

Bolgiano, B., Moran, E., Beresford, N. J., Gao, F., Care, R., Desai, T., ... & Pisal, S. S. (2021). Evaluation of critical quality attributes of a pentavalent (A, C, Y, W, X) meningococcal conjugate vaccine for global use. Pathogens, 10(8), 928. https://doi.org/10.3390/pathogens10080928

Tapia, M. D., Sow, S. O., Naficy, A., Diallo, F., Haidara, F. C., Chaudhari, A., ... & Kulkarni, P. S. (2021). Meningococcal serogroup ACWYX conjugate vaccine in Malian toddlers. New England Journal of Medicine, 384(22), 2115-2123. https://www.nejm.org/doi/10.1056/NEJMoa2013615

Arndt, M. B., Cantera, J. L., Mercer, L. D., Kalnoky, M., White, H. N., Bizilj, G., ... & Choy, R. K. (2020). Validation of the Micronutrient and Environmental Enteric Dysfunction Assessment Tool and evaluation of biomarker risk factors for growth faltering and vaccine failure in young Malian children. PLoS Neglected Tropical Diseases,14(9), e0008711. https://doi.org/10.1371/journal.pntd.0008711

Sherman, A. C., & Stephens, D. S. (2020). Serogroup A meningococcal conjugate vaccines: Building sustainable and equitable vaccine strategies. Expert Review of Vaccines, 19(5), 455-463. https://doi.org/10.1080/14760584.2020.1760097

Read, R. C. (2019). Neisseria meningitidis and meningococcal disease: Recent discoveries and innovations. Current Opinion in Infectious Diseases, 32(6), 601-608.
htps://doi.org/10.1097/QCO.0000000000000606

Shende, N., Karale, A., Marathe, P., Chakraborty, S., Mallya, A. D., & Dhere, R. M. (2019). Quantitation of residual sodium dodecyl sulfate in meningococcal polysaccharide by gas chromatography-mass spectrometry. Biologicals, 60, 68-74. https://doi.org/10.1016/j.biologicals.2019.05.001

Chen, W. H., Neuzil, K. M., Boyce, C. R., Pasetti, M. F., Reymann, M. K., Martellet, L., ... & Alderson, M. R. (2018). Safety and immunogenicity of a pentavalent meningococcal conjugate vaccine containing serogroups A, C, Y, W, and X in healthy adults: A phase 1, single-centre, double-blind, randomised, controlled study. The Lancet Infectious Diseases, 18(10), 1088-1096.
https://doi.org/10.1016/S1473-3099(18)30400-6

Preziosi, M. P., & Greenwood, B. (2018). NmCV-5 meningococcal vaccine: Neisseria meningitidis' nemesis?. The Lancet Infectious Diseases, 18(10), 1049-1050.
https://pubmed.ncbi.nlm.nih.gov/30120070/

Page, A. L., Coldiron, M. E., Gamougam, K., Acyl, M. A., Tamadji, M., Lastrucci, C., ... & Porten, K. (2017). Four years of case‐based surveillance of meningitis following the introduction of MenAfriVac in Moissala, Chad: Lessons learned. Tropical Medicine & International Health, 22(12), 1561-1568.
https://doi.org/10.1111/tmi.12987