The search terms, keywords, and phrases used for each EtR domain (1–7) represent a basic and systematic approach. However, the search may not have captured all relevant articles, reports, or publications available in the literature
Policy Question 1: Should country X recommend Mpox vaccines for populations in the community of high risk of being exposed to Mpox during the current outbreak?
| Population | Populations in the community at high risk of Mpox in outbreak settings |
| Intervention | Administration of the licensed or WHO prequalified Mpox vaccine (MVA-BN [ 2doses]. LC-16 [1 dose] or A-CAM2000 [1 dose]) |
| Comparison | none |
| Outcome | Reduction in incidence of Mpox infection, (hospitalization and death) |
Policy question 2 : Should country X recommend Mpox vaccines for healthcare workers and frontline workers at high risk of being exposed during the current outbreak?
| Population | Healthcare workers and frontline workers at high risk of exposure to Mpox |
| Intervention | Administration of the licensed or WHO prequalified Mpox vaccine (MVA-BN [ 2doses]. LC-16 [1 dose] or A-CAM2000 [1 dose]) |
| Comparison | none |
| Outcome | Reduction in incidence of Mpox infection, (hospitalization and death) |
Domain 1:
Mpox and “disease burden” OR epidemiology OR incidence OR cases OR hospitalization OR case fatality OR “clinical characteristics” OR “cost of health care” OR “alternative prevention”
Domain 2:
Mpox and vaccines and “benefits and harms” OR safety OR efficacy OR effectiveness OR “adverse events”
Domain 3:
Mpox and vaccines and “values and preferences” OR demand
Domain 4:
Mpox and “availability of vaccine” OR “resource use” OR cost-effectiveness
Domain 5:
Mpox and “health equity” OR “ethical or legal implication”
Domain 6:
Mpox and “acceptability of intervention” OR “acceptance of intervention”
Domain 7:
Mpox and feasibility OR “successful implementation” OR “financial barriers” OR “vaccine supply” OR “vaccine use”
Google Scholar
PubMed
WHO
JAMA Network
CDC
Newspaper Source (Ebscohost)
Theses and dissertations