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NISH (NITAG SUPPORT HUB) 3 - Malaria vaccines: Latest publications on Malaria vaccine RTS,S/AS01

This Library Guide is a collection of useful documents & evidence on the efficacy, effectiveness and impact of the RTS,S/AS01 malaria vaccine to support NITAG members and other policy makers throughout Africa with making evidence-based recommendations.

2023 publications

Abuga, K.M., Jones‐Warner, W. and Hafalla, J.C.R., 2021. Immune responses to malaria pre‐erythrocytic stages: implications for vaccine development. Parasite immunology, 43(2), p.e12795. https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pim.12795
 
World Health Organization (WHO). 2020. Malaria: The malaria vaccine implementation programme (MVIP). Questions and answers. https://www.who.int/news-room/questions-and-answers/item/malaria-vaccine-implementation-programme
 
Sagara, I., Zongo, I., Cairns, M., Yerbanga, R.S., Mahamar, A., Nikièma, F., Tapily, A., Sompougdou, F., Diarra, M., Zoungrana, C. and Issiaka, D., 2022. The anti-circumsporozoite antibody response of children to seasonal vaccination with the Rts, S/As01e malaria vaccine. Clinical Infectious Diseases, 75(4), pp.613-622. DOI: 10.1093/cid/ciab1017
 
World Health Organization (WHO), 2020. Malaria Eradication: Benefits. Future Scenarios and Feasibility: A Report of the Strategic Advisory Group on Malaria Eradication. https://www.who.int/publications-detail/strategic-advisory-group-malaria-eradication-executive-summary
 
Vanderberg, J.P., 2009. Reflections on early malaria vaccine studies, the first successful human malaria vaccination, and beyond. Vaccine, 27(1), pp.2-9. doi: 10.1016/j.vaccine.2008.10.028
 
Akalazu, C.N. and Okwa, O.O., Review On Malaria Vaccines: The Panacea for Africa.
https://www.researchgate.net/profile/Omolade-Okwa/publication/368574094_Review_On_Malaria_Vaccines_The_Panacea_for_Africa/links/63ef069419130a1a4a86faa5/Review-On-Malaria-Vaccines-The-Panacea-for-Africa.pdf
 
Mahase, E., 2021. Malaria vaccine becomes first to achieve 75% efficacy goal in trial of children. BMJ: British Medical Journal (Online), 373.
DOI:10.1136/bmj.n1078 (NOT OA)
 
Wadman, M., 1979. First malaria vaccine slashes childhood deaths. Science, pp.357-357. DOI: 10.1126/science.adl5521
 
Cutts, J.C., Agius, P.A., Lin, Z., Powell, R., Moore, K., Draper, B., Simpson, J.A. and Fowkes, F.J., 2020. Pregnancy-specific malarial immunity and risk of malaria in pregnancy and adverse birth outcomes: a systematic review. BMC medicine, 18, pp.1-21 https://link.springer.com/article/10.1186/s12916-019-1467-6
 

Brew, J. and Sauboin, C., 2019. A systematic review of the incremental costs of implementing a new vaccine in the expanded program of immunization in sub-Saharan Africa. MDM Policy & Practice, 4(2), p.2381468319894546. https://doi.org/10.1177/2381468319894546

Githang'a, D., Anzala, O., Mutegi, C. and Agweyu, A., 2019. The effects of exposures to mycotoxins on immunity in children: A systematic review. Current problems in pediatric and adolescent health care, 49(5), pp.109-116. (NOT OA)

Dimala, C.A., Kika, B.T., Kadia, B.M. and Blencowe, H., 2018. Current challenges and proposed solutions to the effective implementation of the RTS, S/AS01 Malaria Vaccine Program in sub-Saharan Africa: A systematic review. PloS one, 13(12), p.e0209744. DOI: 10.1371/journal.pone.0209744

Lindsey, B.B., Armitage, E.P., Kampmann, B. and de Silva, T.I., 2019. The efficacy, effectiveness, and immunogenicity of influenza vaccines in Africa: a systematic review. The Lancet Infectious diseases, 19(4), pp.e110-e119. (NOT OA)

Degarege, A., Gebrezgi, M.T., Ibanez, G., Wahlgren, M. and Madhivanan, P., 2019. Effect of the ABO blood group on susceptibility to severe malaria: a systematic review and meta-analysis. Blood reviews, 33, pp.53-62. (NOT OA)

Brickley, E.B., Coulibaly, M., Gabriel, E.E., Healy, S.A., Hume, J.C., Sagara, I., Traore, S.F., Doumbo, O. and Duffy, P.E., 2016. Utilizing direct skin feeding assays for development of vaccines that interrupt malaria transmission: a systematic review of methods and case study. Vaccine, 34(48), pp.5863-5870. DOI: 10.1016/j.vaccine.2016.10.027

Oyo‐Ita, A., Wiysonge, C.S., Oringanje, C., Nwachukwu, C.E., Oduwole, O. and Meremikwu, M.M., 2016. Interventions for improving coverage of childhood immunisation in low‐and middle‐income countries. Cochrane Database of Systematic Reviews, (7).https://scholar.sun.ac.za/items/00317942-258d-4e5b-bebb-041befc35f4a

Mbuagbaw, L., Medley, N., Darzi, A.J., Richardson, M., Garga, K.H. and Ongolo‐Zogo, P., 2015. Health system and community level interventions for improving antenatal care coverage and health outcomes. Cochrane Database of Systematic Reviews, (12).  DOI: 10.1002/14651858.CD010994.pub2

Matangila, J.R., Mitashi, P., Inocêncio da Luz, R.A., Lutumba, P.T. and Van Geertruyden, J.P., 2015. Efficacy and safety of intermittent preventive treatment for malaria in schoolchildren: a systematic review. Malaria journal, 14, pp.1-12.   DOI: 10.1186/s12936-015-0988-5

Agnandji, S.T., Fernandes, J.F., Bache, E.B. and Ramharter, M., 2015. Clinical development of RTS, S/AS malaria vaccine: a systematic review of clinical Phase I–III trials. Future microbiology, 10(10), pp.1553-1578. (NOT OA)

 

 

 

 

 

 

 

Systematic Reviews

Yihunie, W., Kebede, B., Tegegne, B.A., Getachew, M., Abebe, D., Aschale, Y., Belew, H. and Bahiru, B., 2023. Systematic Review of Safety of RTS, S with AS01 and AS02 Adjuvant Systems Using Data from Randomized Controlled Trials in Infants, Children, and Adults. Clinical Pharmacology: Advances and Applications, pp.21-32.     https://www.tandfonline.com/doi/full/10.2147/CPAA.S400155

Sulaiman, S.K., Musa, M.S., Tsiga-Ahmed, F.I., Dayyab, F.M., Sulaiman, A.K. and Bako, A.T., 2022. A systematic review and meta-analysis of the prevalence of caregiver acceptance of malaria vaccine for under-five children in low-income and middle-income countries (LMICs). Plos one, 17(12), p.e0278224.   https://doi.org/10.1371/journal.pone.0278224

Takashima, E., Kanoi, B.N., Nagaoka, H., Morita, M., Hassan, I., Palacpac, N.M., Egwang, T.G., Horii, T., Gitaka, J. and Tsuboi, T., 2022. Meta-Analysis of Human Antibodies Against Plasmodium falciparum Variable Surface and Merozoite Stage Antigens. Frontiers in Immunology, 13, p.887219. https://doi.org/10.3389/fimmu.2022.887219

Oguike, O.E., Ugwuishiwu, C.H., Asogwa, C.N., Nnadi, C.O., Obonga, W.O. and Attama, A.A., 2022. Systematic review on the application of machine learning to quantitative structure–activity relationship modeling against Plasmodium falciparum. Molecular Diversity, 26(6), pp.3447-3462. (NOT OA)

Shibeshi, W., Bagchus, W., Yalkinoglu, Ö., Tappert, A., Engidawork, E. and Oeuvray, C., 2021. Reproducibility of malaria sporozoite challenge model in humans for evaluating efficacy of vaccines and drugs: a systematic review. BMC Infectious Diseases, 21(1), pp.1-15. https://doi.org/10.1186/s12879-021-06953-4https://doi.org/10.1186/s12879-021-06953-4

Banda, G.T., Deribe, K. and Davey, G., 2021. How can we better integrate the prevention, treatment, control and elimination of neglected tropical diseases with other health interventions? A systematic review. BMJ Global Health, 6(10), p.e006968. DOI: 10.1136/bmjgh-2021-006968

Nnaji, C.A., Wiysonge, C.S., Okeibunor, J.C., Malinga, T., Adamu, A.A., Tumusiime, P. and Karamagi, H., 2021. Implementation research approaches to promoting universal health coverage in Africa: a scoping review. BMC health services research, 21, pp.1-17.  https://link.springer.com/article/10.1186/s12913-021-06449-6

Meteke, S., Stefopulos, M., Als, D., Gaffey, M.F., Kamali, M., Siddiqui, F.J., Munyuzangabo, M., Jain, R.P., Shah, S., Radhakrishnan, A. and Ataullahjan, A., 2020. Delivering infectious disease interventions to women and children in conflict settings: a systematic review. BMJ Global Health, 5(Suppl 1), p.e001967.  DOI: 10.1136/bmjgh-2019-001967

Muthui, M.K., Kamau, A., Bousema, T., Blagborough, A.M., Bejon, P. and Kapulu, M.C., 2019. Immune responses to gametocyte antigens in a malaria endemic population—the African falciparum context: a systematic review and meta-analysis. Frontiers in immunology, 10, p.2480. DOI: 10.3389/fimmu.2019.02480