Skip to Main Content

NISH (NITAG SUPPORT HUB) 3 - Malaria vaccines: Ghana

This Library Guide is a collection of useful documents & evidence on the efficacy, effectiveness and impact of the RTS,S/AS01 malaria vaccine to support NITAG members and other policy makers throughout Africa with making evidence-based recommendations.

Malaria vaccine

Organisation mondiale de la Santé, O. and World Health Organization, 2022. Malaria vaccine: WHO position paper–March 2022–Rapport mensuel des cas de dracunculose, janvier 2022. Weekly Epidemiological Record= Relevé épidémiologique hebdomadaire, 97(09), pp.60-78.
https://www.who.int/publications/i/item/who-wer9709-61%E2%80%9380
 
World Health Organization, 2022. WHO guidelines for malaria, 3 June 2022 (No. WHO/UCN/GMP/2022.01 Rev. 2). World Health Organization.
https://www.who.int/publications/i/item/guidelines-for-malaria
 
World Health Organization. 2021. Infographic of the RTS,S Malaria vaccine. A WHO recommended vaccine for added protection against malaria to improve child health, save lives and strengthen malaria control in Africa and in other regions with moderate to high malaria transmission.
https://cdn.who.int/media/docs/default-source/immunization/mvip/who-mvip-infographic-april-2022.pdf?sfvrsn=b9a755ae_1
 
World Health Organization. 2022. Malaria vaccine implementation programme.
https://www.who.int/initiatives/malaria-vaccine-implementation-programme
 
Penny, M.A., Kelly, S.L., Shattock, A.J., Ross, A., Malinga, J., Winskill, P., Hogan, A., Mulongeni, P., Thompson, H., Verity, B. and Ghani, A.,2021. Modelled public health impact and cost effectiveness estimates of RTS,S/AS01 malaria vaccine in perennial and seasonal settings. WHO Guidelines for malaria.
https://zenodo.org/record/6395853
 
Villanueva, G., Henschke, N., Hamel, C. and Buckley, B., Annex 9a: Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) Evidence summary table. RTS, 1, p.1.
doi.org/10.5281/zenodo.6395853
 
World Health Organization. 2022. Q&A on the RTS,S malaria vaccine, the WHO vaccine recommendation and next steps.
https://www.who.int/news-room/questions-and-answers/item/q-a-on-rts-s-malaria-vaccine
 
Galactionova, K., Bertram, M., Lauer, J. and Tediosi, F., 2015. Costing RTS, S introduction in Burkina Faso, Ghana, Kenya, Senegal, Tanzania, and Uganda: a generalizable approach drawing on publicly available data. Vaccine, 33(48), pp.6710-6718.
https://doi.org/10.1016/j.vaccine.2015.10.079
 
RTS,S/AS01 SAGE/MPAG Working Group. (2022). Full Evidence Report on the RTS,S/AS01 Malaria Vaccine. Zenodo. https://doi.org/10.5281/zenodo.6394605
 
Milligan P, & Moore K. (2022). Statistical report on the results of the RTS,S/AS01 Malaria Vaccine Pilot Evaluation 24 months after the vaccine was introduced (September 2021, v1.2). Zenodo. https://doi.org/10.5281/zenodo.6395806
 
Rts, S.C.T.P., 2015. Efficacy and safety of RTS, S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial. The Lancet, 386(9988), pp.31-45. doi: 10.1016/S0140-6736(15)60721-8
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626001/
 
PATH, Liverpool School of Tropical Medicine (Kenya), Malawi-Liverpool Wellcome Trust (Malawi), & University of Health and Allied Sciences (Ghana). (2022). Health Utilisation Study (HUS) Round 2 - cross-country report on findings from the Primary Child Caregiver cohort sample. Zenodo. https://doi.org/10.5281/zenodo.6395820
 
Chandramohan, D., Zongo, I., Sagara, I., Cairns, M., Yerbanga, R.S., Diarra, M., Nikiema, F., Tapily, A., Sompougdou, F., Issiaka, D. and Zoungrana, C., 2021. Seasonal malaria vaccination with or without seasonal malaria chemoprevention. New England Journal of Medicine, 385(11), pp.1005-1017. DOI: 10.1056/NEJMoa2026330
 
Neafsey, D.E., Juraska, M., Bedford, T., Benkeser, D., Valim, C., Griggs, A., Lievens, M., Abdulla, S., Adjei, S., Agbenyega, T. and Agnandji, S.T., 2015. Genetic diversity and protective efficacy of the RTS, S/AS01 malaria vaccine. New England Journal of Medicine, 373(21), pp.2025-2037. (NOT OA)
 
Ansong, D., Asante, K.P., Vekemans, J., Owusu, S.K., Owusu, R., Brobby, N.A., Dosoo, D., Osei-Akoto, A., Osei-Kwakye, K., Asafo-Adjei, E. and Boahen, K.O., 2011. T cell responses to the RTS, S/AS01E and RTS, S/AS02D malaria candidate vaccines administered according to different schedules to Ghanaian children. PLoS One, 6(4), p.e18891.

https://doi.org/10.1371/journal.pone.0018891

 
Owusu-Agyei, S., Ansong, D., Asante, K., Kwarteng Owusu, S., Owusu, R., Wireko Brobby, N.A., Dosoo, D., Osei Akoto, A., Osei-Kwakye, K., Adjei, E.A. and Boahen, K.O., 2009. Randomized controlled trial of RTS, S/AS02D and RTS, S/AS01E malaria candidate vaccines given according to different schedules in Ghanaian children. PLoS One, 4(10), p.e7302.

https://doi.org/10.1371/journal.pone.0007302