Skip to Main Content

NISH (NITAG Support Hub) 2: Covid-19 vaccine hesitancy/confidence in Africa

This Library Guide contains published and unpublished information on vaccine hesitancy and related issues in the context of COVID-19 vaccination in Subsaharan Africa

Covid-19 AND ("Vaccine hesitancy" OR "vaccine refusal" OR "vaccine acceptance" OR "vaccine confidence")

Alimohamadi, Y., Hosamirudsari, H., Hesari, E. and Sepandi, M., 2022. Global COVID-19 vaccine acceptance rate: A systematic review and meta-analysis. Journal of Public Health, pp.1-13. (not OA)

Bama, H.K.N., Sunday, T. and Makuzva, W., 2022. What innovations would enable the tourism and hospitality industry in Africa to re-build?. Worldwide Hospitality and Tourism Themes, (ahead-of-print).
Gilmore, B., Gerlach, N., Lopes, C.A., Bhattacharyya, S., de Claro, V., Ndejjo, R., Mago, E.N. and Tchetchia, A., 2022. Community engagement to support COVID-19 vaccine uptake: a living systematic review protocol. BMJ open, 12(9), p.e063057.

Introduction Widespread vaccination against COVID-19 is one of the most effective ways to control, and ideally, end the global COVID-19 pandemic. Vaccine hesitancy and vaccine rates vary widely across countries and populations and are influenced by complex sociocultural, political, economic and psychological factors. Community engagement is an integral strategy within immunisation campaigns and has been shown to improve vaccine acceptance. As evidence on community engagement to support COVID-19 vaccine uptake is emerging and constantly changing, research that lessens the knowledge-to-practice gap by providing regular and up-to-date evidence on current best-practice is essential.

Methods and analysis A living systematic review will be conducted which includes an initial systematic review and bimonthly review updates. Searching and screening for the review and subsequent updates will be done in four streams: a systematic search of six databases, grey literature review, preprint review and citizen sourcing. The screening will be done by a minimum of two reviewers at title/abstract and full-text in Covidence, a systematic review management software. Data will be extracted across predefined fields in an excel spreadsheet that includes information about article characteristics, context and population, community engagement approaches, and outcomes. Synthesis will occur using the convergent integrated approach. We will explore the potential to quantitatively synthesise primary outcomes depending on heterogeneity of the studies.

Ethics and dissemination The initial review and subsequent bimonthly searches and their results will be disseminated transparently via open-access methods. Quarterly briefs will be shared on the reviews’ social media platforms and across other interested networks and repositories. A dedicated web link will be created on the Community Health-Community of Practice site for sharing findings and obtaining feedback. A mailing list will be developed and interested parties can subscribe for updates.

Mungmunpuntipantip, R. and Wiwanitkit, V., 2022. Addressing COVID-19 vaccine hesitancy. Human Vaccines & Immunotherapeutics, p.2124090.
Van De Pas, R., Widdowson, M.A., Ravinetto, R., N Srinivas, P., Ochoa, T.J., Fofana, T.O. and Van Damme, W., 2022. COVID-19 vaccine equity: a health systems and policy perspective. Expert review of vaccines, 21(1), pp.25-36.
Ledford, C.J., Cafferty, L.A., Moore, J.X., Roberts, C., Whisenant, E.B., Garcia Rychtarikova, A. and Seehusen, D.A., 2022. The dynamics of trust and communication in COVID-19 vaccine decision making: A qualitative inquiry. Journal of Health Communication, pp.1-10.
Theophilus, N., Rios-Bedoya, C. and Bachuwa, G., 2022. COVID-19 Vaccine Survey among Healthcare Workers. A Community Experience. Spartan Medical Research Journal, 7(2). (Not OA)
Introduction : In December 2019, the coronavirus (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) made its first appearance in Wuhan, China with a pandemic declared by March 2020. As the death toll continued to rise, the Centers for Diseases Control and Prevention (CDC) recommended healthcare workers to strongly encourage the general population to receive COVID-19 vaccinations. For this to be effective, it is important to understand the general perceptions of the health care workers and persons associated with the healthcare industry towards their acceptance of the vaccine.
Wiysonge, C.S., Ndwandwe, D., Ryan, J., Jaca, A., Batouré, O., Anya, B.P.M. and Cooper, S., 2022. Vaccine hesitancy in the era of COVID-19: could lessons from the past help in divining the future?. Human vaccines & immunotherapeutics, 18(1), pp.1-3.
Sallam, M., 2021. COVID-19 vaccine hesitancy worldwide: a concise systematic review of vaccine acceptance rates. Vaccines9(2), p.160.
Razai, M.S., Oakeshott, P., Esmail, A., Wiysonge, C.S., Viswanath, K. and Mills, M.C., 2021. COVID-19 vaccine hesitancy: the five Cs to tackle behavioural and sociodemographic factors. Journal of the Royal Society of Medicine, 114(6), pp.295-298. (Not OA)

Serwaa, D., Lamptey, E. and Senkyire, E.K., 2021. Increasing COVID-19 vaccine acceptance among the general population while maintaining autonomy. Human Vaccines & Immunotherapeutics, 17(12), pp.5139-5141. (Not OA)

Greenhawt, M., Abrams, E.M., Shaker, M., Chu, D.K., Khan, D., Akin, C., Alqurashi, W., Arkwright, P., Baldwin, J.L., Ben-Shoshan, M. and Bernstein, J., 2021. The risk of allergic reaction to SARS-CoV-2 vaccines and recommended evaluation and management: a systematic review, meta-analysis, GRADE assessment, and international consensus approach. The Journal of Allergy and Clinical Immunology: In Practice9(10), pp.3546-3567 (NOT OA)

Reñosa, M.D.C., Landicho, J., Wachinger, J., Dalglish, S.L., Bärnighausen, K., Bärnighausen, T. and McMahon, S.A., 2021. Nudging toward vaccination: a systematic review. BMJ global health6(9), p.e006237.

Puri, N., Coomes, E.A., Haghbayan, H. and Gunaratne, K., 2020. Social media and vaccine hesitancy: new updates for the era of COVID-19 and globalized infectious diseases. Human vaccines & immunotherapeutics, 16(11), pp.2586-2593. (Not OA)

Cooper, S., Betsch, C., Sambala, E.Z., Mchiza, N. and Wiysonge, C.S., 2018. Vaccine hesitancy–a potential threat to the achievements of vaccination programmes in Africa. Human vaccines & immunotherapeutics, 14(10), pp.2355-2357.


Abdelmoneim, S.A., Sallam, M., Hafez, D.M., Elrewany, E., Mousli, H.M., Hammad, E.M., Elkhadry, S.W., Adam, M.F., Ghobashy, A.A., Naguib, M. and Nour El-Deen, A.E.S., 2022. COVID-19 vaccine booster dose acceptance: Systematic review and meta-analysis. Tropical Medicine and Infectious Disease, 7(10), p.298.

Google Scholar

Galanis, P., Vraka, I., Katsiroumpa, A., Siskou, O., Konstantakopoulou, O., Katsoulas, T., Mariolis-Sapsakos, T. and Kaitelidou, D., 2022. COVID-19 Vaccine Uptake among Healthcare Workers: A Systematic Review and Meta-Analysis. Vaccines, 10(10), p.1637.